Cardiac specific creatine phosphokinase isoenzyme in the diagnosis of acute myocardial infarction.

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Cardiac specific creatine phosphokinase isoenzyme in the diagnosis of acute myocardial infarction.

The specific and sensitivity of serum creatine phosphokinase cardiac specific isoenzyme (MB) in the diagnosis of acute myocardial infarction (AMI) was evaluated. An ion-exchange chromatographic technique was used to isolate MB. Sera layered on mini-columns of DEAE-Sephadex were eluted with Tris-buffered sodium chloride. Quantification of isolated MB was performed by creatine phosphokinase (CPK)...

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Cardiac Specific Creatine Phosphokinase

The specificity and sensitivity of serum creatine phosphokinase cardiac specific isoenzyme (MB) in the diagnosis of acute myocardial infarction (AM I) was evaluated. An ion-exchange chromatographic technique was used to isolate MB. Sera layered on mini-columns of DEAE-Sephadex were eluted with Tris-buffered sodium chloride. Quantification of isolated MB was performed by creatine phosphokinase (...

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Unstimulated whole saliva creatine phosphokinase in acute myocardial infarction.

OBJECTIVE Accurate and rapid diagnosis of acute myocardial infarction (MI) is of major medical and economic importance. The objective of this study was to identify unstimulated whole saliva creatine phosphokinase (CPK) in patients with acute MI. SUBJECTS AND METHODS A case-control study was carried out in 30 normal healthy individuals and 30 patients with acute MI were hospitalized in CCU of ...

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Creatine kinase MB isoenzyme studies in diagnosis of myocardial infarction.

Serial measurements of the MB isoenzyme of creatine kinase, total creatine kinase, aspartate mainotransferase, and urea stable lactate dehydrogenase have been made in the serum of a series of 139 patients admitted with a diagnosis of suspected myocardial infarction. Serum MB isoenzyme measurements have also been made on postoperative surgical patients and patients with medical disorders known t...

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Serum creatine phosphokinase estimations in myocardial infarction.

Since the initial report on the clinical value of serum glutamic oxalacetic transaminase (SGOT) determinations in the diagnosis of myocardial infarction (LaDue, Wroblewski, and Karmen, 1954), a considerable amount of work has been done on the blood levels of other enzymes liberated from necrosed heart cells. Because of lack of specificity and difficulty of estimation, very few other enzyme esti...

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ژورنال

عنوان ژورنال: Circulation

سال: 1975

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.51.5.855